Dirt cheap whole genome re-sequencing
When writing grant applications I’ve been saying that we could expect whole genome re-sequencing in association mapping studies to be cost effective within the decade. I’m beginning to think that a decade is rather pessimistic.
The cost of re-sequencing is now down to $100,000.
Sure, that is about a factor of 100 more than just getting the SNPs covering your genome and probably tagging most interesting genetic factors we know about, but I would no longer be surprised if the cost would drop to $1000 for re-sequencing within a year, and $1000 was cheap enough for chip based whole genome association mapping studies, so it will be cheap enough for re-sequencing studies.
You can find more on the dropping cost of re-sequencing on Eye on DNA: Whole Genome Sequencing Costs Continue to Drop.
I’d better get cracking on developing analysis methods that can then actually analyse such data…